Marileila Varella-Garcia Selected Research

Ligands

1/2016	A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
7/2015	Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer.
8/2009	HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.

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Marileila Varella-Garcia Research Topics

Disease

66	Neoplasms (Cancer) 10/2020 - 05/2002
53	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 02/2002
34	Lung Neoplasms (Lung Cancer) 01/2022 - 02/2002
9	Adenocarcinoma of Lung 10/2020 - 08/2008
9	Colorectal Neoplasms (Colorectal Cancer) 01/2016 - 06/2010
7	Disease Progression 06/2016 - 09/2004
7	Breast Neoplasms (Breast Cancer) 01/2013 - 02/2002
5	Neoplasm Metastasis (Metastasis) 01/2016 - 11/2003
5	Squamous Cell Carcinoma of Head and Neck 10/2013 - 08/2006
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2018 - 10/2003
4	Sarcoma (Soft Tissue Sarcoma) 01/2016 - 09/2012
3	Carcinoma (Carcinomatosis) 01/2018 - 08/2006
3	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 09/2004
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 07/2015 - 05/2002
2	Glioblastoma (Glioblastoma Multiforme) 01/2019 - 01/2016
2	Ovarian Neoplasms (Ovarian Cancer) 06/2016 - 12/2015
2	Neuroblastoma 01/2016 - 02/2015
2	Carcinogenesis 01/2016 - 05/2003
2	Adenocarcinoma 04/2013 - 04/2011
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2013 - 06/2009
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2011 - 05/2008
2	Lymphatic Metastasis 08/2008 - 08/2006
2	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 10/2005 - 10/2003
1	Odontogenic Cysts (Keratocyst) 02/2018
1	Acne Vulgaris 01/2018
1	Fatigue 01/2018
1	Exanthema (Rash) 01/2018
1	Melanoma (Melanoma, Malignant) 01/2017
1	Residual Neoplasm 01/2017
1	Polyploidy 01/2016
1	Confusion (Bewilderment) 01/2016
1	Dyspnea (Shortness of Breath) 10/2015

Drug/Important Bio-Agent (IBA)

40	ErbB Receptors (EGF Receptor)IBA 06/2016 - 10/2003
24	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2002
21	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2006
18	Tyrosine Kinase InhibitorsIBA 01/2018 - 08/2005
16	Gefitinib (Iressa)FDA Link 06/2009 - 05/2005
15	CrizotinibIBA 01/2017 - 10/2010
12	Phosphotransferases (Kinase)IBA 01/2018 - 09/2012
12	Anaplastic Lymphoma KinaseIBA 12/2016 - 12/2009
8	Erlotinib Hydrochloride (CP 358,774)FDA Link 06/2016 - 12/2006
7	Biological ProductsIBA 02/2018 - 05/2006
6	Cetuximab (Erbitux)FDA Link 01/2022 - 04/2008
6	Messenger RNA (mRNA)IBA 02/2017 - 04/2005
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2020 - 12/2006
5	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2004
5	Pharmaceutical PreparationsIBA 01/2017 - 09/2012
5	Trastuzumab (Herceptin)FDA Link 06/2006 - 02/2002
4	Formaldehyde (Formol)FDA Link 10/2020 - 08/2006
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2015 - 05/2005
4	Epidermal Growth Factor (EGF)IBA 01/2013 - 08/2003
3	ParaffinIBA 10/2020 - 08/2006
3	PlatinumIBA 06/2016 - 08/2011
3	LigandsIBA 01/2016 - 08/2009
3	Indicators and Reagents (Reagents)IBA 01/2016 - 09/2006
3	Phosphatidylinositols (Phosphatidylinositol)IBA 03/2014 - 05/2012
3	Monoclonal AntibodiesIBA 02/2012 - 02/2002
3	Gemcitabine FDA Link 06/2009 - 05/2002
2	AntibodiesIBA 01/2018 - 03/2015
2	RNA (Ribonucleic Acid)IBA 01/2017 - 09/2006
2	human ERBB2 proteinIBA 03/2016 - 02/2015
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2015 - 04/2008
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 07/2015 - 06/2009
2	Telomerase (Telomerase Reverse Transcriptase)IBA 04/2015 - 10/2006
2	ON 01910IBA 03/2014 - 10/2013
2	CateninsIBA 03/2014 - 01/2011
2	Polo-Like Kinase 1IBA 03/2014 - 10/2013
2	Tyrosine (L-Tyrosine)FDA Link 01/2014 - 08/2006
2	saracatinibIBA 05/2012 - 08/2010
2	Insulin (Novolin)FDA Link 02/2012 - 05/2010
2	Paclitaxel (Taxol)FDA LinkGeneric 09/2011 - 10/2008
2	Carboplatin (JM8)FDA LinkGeneric 09/2011 - 10/2008
2	Transforming Growth Factor alpha (TGF-alpha)IBA 08/2009 - 06/2009
2	CortactinIBA 06/2009 - 08/2006
2	Cytotoxins (Cytolysins)IBA 06/2009 - 09/2004
2	Hormones (Hormone)IBA 09/2004 - 11/2003
1	necitumumabIBA 01/2018
1	rho-Associated KinasesIBA 02/2017
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2017
1	ponatinibIBA 01/2017
1	osimertinibIBA 01/2017
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 12/2016
1	c-Mer Tyrosine KinaseIBA 01/2016
1	Notch1 ReceptorIBA 01/2016
1	UNC2025IBA 01/2016
1	Propidium (Propidium Iodide)IBA 01/2016
1	Oncogene Proteins (Oncogene Protein)IBA 10/2015
1	TropomyosinIBA 10/2015
1	larotrectinibIBA 10/2015
1	Tumor Biomarkers (Tumor Markers)IBA 10/2015
1	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 09/2015
1	Mitogen-Activated Protein KinasesIBA 09/2015
1	Dual Specificity Phosphatase 1IBA 09/2015
1	ras ProteinsIBA 09/2015

Therapy/Procedure

38	Therapeutics 01/2022 - 01/2003
13	Drug Therapy (Chemotherapy) 01/2022 - 05/2007
2	Immunotherapy 01/2016 - 03/2006
2	Chemoprevention 08/2008 - 03/2007
1	Subcutaneous Injections 01/2016
1	Ligation 10/2015